In theory, it acts primarily by increasing the neurotransmitters serotonin, dopamine, and noradrenaline activity and belongs to the substituted amphetamine classes. Researchers have reported that 5-MAPB has the same stimulant and hallucinogenic outcomes.

5-MAPB, or 5-(2-methylaminopropyl)benzofuran, is a synthetic entactogenic and stimulant research compound belonging to the benzofuran class. It is structurally related to both 6-APB and MDMA, making it a compound of great interest in pharmacology, forensic science, and neurochemistry. Since its introduction to research communities, 5-MAPB has been studied extensively for its unique effects on serotonin pathways and receptor binding activity.

In laboratory research, 5-MAPB functions primarily as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). This allows researchers to analyze its effects on neurotransmitter modulation, particularly in relation to serotonin 5-HT2 receptors. Such studies are vital for understanding the mechanisms of entactogenic compounds, their similarities with MDMA, and their distinct differences in potency and duration.

Forensic laboratories uses as a reference standard compound, aiding in chromatographic analysis, mass spectrometry validation, and toxicological profiling of seized materials. Its presence in forensic casework has made it an important compound for developing accurate detection protocols and enhancing analytical methodologies used in modern toxicology labs.

Researchers also employ 5-MAPB in structure-activity relationship (SAR) studies, where it is compared with related entactogens such as 6-APB, MDAI, and MDMA. These studies shed light on how minor molecular modifications influence receptor binding, stimulant properties, and entactogenic effects. By exploring its molecular structure, scientists gain deeper insights into benzofuran derivatives and their role in neuropharmacological research.

The importance of authenticity and purity cannot be overstated when working with 5-MAPB. Impure or counterfeit samples can not only lead to incorrect experimental results but may also undermine scientific credibility. Laboratories must ensure that all 5-MAPB samples are sourced from trusted suppliers offering verified purity, with analytical reports such as HPLC and GC-MS validation. This guarantees reproducible outcomes and enhances the reliability of published research.

5-MAPB is also a compound of interest in comparative pharmacology, where it serves as a benchmark against both classic entactogens and modern synthetic analogues. Its benzofuran backbone gives it unique receptor interactions, making it essential for studying entactogen diversity and neurochemical profiles.

It is crucial to emphasize that 5-MAPB is strictly a research chemical not intended for human consumption. Laboratories using C12H15NO must follow strict handling protocols, safe storage practices, and compliance with legal regulations. As synthetic benzofurans are often subject to controlled substance scheduling in some jurisdictions, researchers must remain aware of local regulatory frameworks.

In conclusion, 5-MAPB is a highly valuable laboratory compound that plays an important role in neuropharmacological studies, forensic toxicology, and analytical chemistry. Its similarities to entactogenic compounds, coupled with its unique molecular structure, make it an essential research tool. By sourcing authentic, lab-verified C12H15NO, researchers can ensure accurate results, avoid counterfeit powders, and contribute to the advancement of stimulant and entactogen research worldwide.

What is the purpose of 5-MAPB?

Because 5-MAPB is a 2C receptor agonist, it would be suitable to begin studies using this 2C receptor injected on a synthetic membrane. Because benzofuran compound is so new, it may be important to report its selectivity for this receptor by conducting a receptor mapping study with a radiolabelled variant of C12H15NO. Competitive ligand binding tests with different 2C ligands could be included in future research. Unless a specific home office license is acquired, C12H15NO may only be utilized for in vitro (outside living creature) research.

Also, 5-MAPB could be utilized as a primary reagent as well as a reference sample for analytical libraries such as GC/MS, HPLC, NMR, and FTIR analysis. Toxicologists and forensic scientists may benefit from this.

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This compound is known for its stimulating, euphoric, and entactogenic effects that are capable of acting as a quasi-substitute for MDMA proper, which has resulted in its rise in popularity as a research chemical that is easily accessible through the use of online vendors. It has been sold as a designer drug since 2010. Purchase 5-C12H15NO is commonly found as the succinate and hydrochloride salt. The hydrochloride salt is 10% more potent by the mass so doses should be adjusted accordingly.

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5-(2-methylaminopropyl) benzofuran, or 5-MAPB, is a substituted benzofuran and phenethylamine. It is comprised of an N-methylated ethylamine chain and a furan ring attached to a central benzene ring.

Ensure to store the 5-MAPB powder in a dry and cool place for maximum shelf-life. When handling research chemicals ensure to always take the proper precautions in the laboratory like wiping down surfaces and wearing gloves, a mask & protective clothing.

SUBSTANCE IDENTIFICATION:

5-MAPB has formal name: 1-(Benzofuran-5-yl)-N-methylpropan-2-amine. The chemical formula for 5-MAPB is C12H15NO with a molecular weight of 225.7

TOXICOLOGY OF 5-MAPB:

The toxicity and long-term health effects of recreational 5-MAPB use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown.

WHERE TO BUY 5-MAPB?

In our store ketams you can buy online pure 5-MAPB in bulk, with free shipping and a delivery guarantee. Here at Ketams Clinic, you can buy Research Chemicals in crystal, powder, and liquid form.